It seems work... [Lzy1 at Lzy ~]$ cat /proc/asound/cards 0 [SB ]: HDA-Intel - HDA ATI SB HDA ATI SB at 0xfe8f4000 irq 16 1 [C400 ]: USB-Audio - Fast Track C400 M-Audio Fast Track C400 at usb-0000:00:13.2-3, high speed but I cannot find fast track c400 on the sound setting panel.